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| July 20, 2026

Biostimulation and Growth Regulation: The Science
Behind a Synthetic Phytohormone Concentrate

Biostimulation and Growth Regulation: The Science
Behind a Synthetic Phytohormone Concentrate

AUTHORS | Parra, J.; Quirós, J.; Barrantes, D. Formulaciones Químicas S.A.: Puntarenas, Costa Rica./span>

ABSTRACT

Modern agricultural productivity depends on the efficient use of Plant Growth Regulators (PGRs). However, phytohormones such as auxins, gibberellins, and cytokinins present significant formulation challenges due to their limited water solubility and susceptibility to hydrolysis in aqueous media. This article describes the development and scientific rationale of a non-aqueous concentrate containing three phytohormones (cytokinins, GA3, and IBA/IAA), stabilized through a ternary solvent matrix. The invention is based on manipulating the dielectric constant (ε) of the medium by employing a three-solvent system with distinct polarities (low, intermediate, and high), thereby broadening the range of intermolecular interactions and ensuring a favourable solvation environment for each synthetic plant hormone.

INTRODUCTION

Plant Growth Regulators (PGRs) are organic compounds that, at very low concentrations, can modify or partially or completely inhibiting the physiological development of plants. Unlike nutrients, these molecules function as chemical messengers that activate or repress specific genes, coordinating processes ranging from seed germination to fruit maturation. Modern biotechnology has established these substances as valuable tools for improving crop productivity and quality by regulating the production of secondary metabolites and optimizing harvest timing.

From a technical standpoint, a plant hormone (phytohormone) is synthesized naturally by the plant, whereas plant growth regulators are synthetic analogues, often exhibiting greater biological activity, that mimic the physiological functions of their corresponding endogenous phytohormones. The effectiveness of these compounds depends on both the application rate and timing, but more importantly on the formulation’s ability to maintain the active molecule in a stable, bioavailable form throughout the application process. The biosynthesis and stability of these hormones are highly sensitive to environmental conditions such as pH and water availability, factors that likewise influence the efficacy of exogenously applied plant growth regulators.

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